SNARE-Targeting Peptide for Softer Expression Lines and Smoother Skin

PeptiSmooth™ delivers Acetyl Hexapeptide-8, a rigorously studied signal peptide that topically modulates the neuromuscular contraction signals responsible for dynamic expression lines — without needles, downtime, or systemic effects.

By mimicking the N-terminus of SNAP-25, a key protein in the SNARE complex, PeptiSmooth™ reduces the intensity of repetitive facial muscle contractions that progressively deepen crow's feet, forehead lines, and frown lines. Published clinical data confirms a measurable 30% reduction in wrinkle depth with consistent use.

Why PeptiSmooth™

• Targets expression lines at the source – modulates SNARE-mediated acetylcholine release at the neuromuscular junction
• Clinically measured results – 30% wrinkle depth reduction documented in published peer-reviewed research
• Non-invasive daily use – topical application with no systemic mechanism, no downtime, no professional administration
• High efficacy at low dose – effective at 5–10 ppm; suitable for targeted eye creams and precision serums
• Clean & globally compliant – synthetic, vegan, cruelty-free, free of neurotoxins

Formulation Advantages

PeptiSmooth™ is water-soluble and odorless, performing without pH sensitivity (stable at 4.5–7.0). At use concentrations, it contributes no viscosity or color and integrates cleanly into eye creams, expression-focused serums, primers, and light moisturizers.